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1

Leptin revisited: its mechanism of action and potential for treating diabetes

Coppari, Roberto, Bjørbæk, Christian

Journal:

Nature Reviews Drug Discovery

Year:

2012

Language:

english

File:

PDF, 1.39 MB

english, 2012

2

Identification of novel hypothalamic genes that are regulated by leptin and play a role in development of leptin-resistance and obesity

Bjørbæk, Christian, Flier, Jeffrey S.

Journal:

Nature Genetics

Year:

1999

Language:

english

File:

PDF, 122 KB

english, 1999

3

Identification of SOCS-3 as a Potential Mediator of Central Leptin Resistance

Christian Bjørbæk, Joel K Elmquist, J.Daniel Frantz, Steven E Shoelson, Jeffrey S Flier

Journal:

Year:

1998

Language:

english

File:

PDF, 429 KB

english, 1998

4

The role of GluN2A and GluN2B NMDA receptor subunits in AgRP and POMC neurons on body weight and glucose homeostasis

Üner, Aykut, Gonçalves, Gabriel H.M., Li, Wenjing, Porceban, Matheus, Caron, Nicole, Schönke, Milena, Delpire, Eric, Sakimura, Kenji, Bjørbæk, Christian

Journal:

Molecular Metabolism

Year:

2015

Language:

english

File:

PDF, 2.84 MB

english, 2015

5

Characterizaton of Short Isoforms of the Leptin Receptor in Rat Cerebral Microvessels and of Brain Uptake of Leptin in Mouse Models of Obesity

Hileman, Stanley M., Pierroz, Dominique D., Masuzaki, Hiroaki, Bjørbæk, Christian, El-Haschimi, Karim, Banks, William A., Flier, Jeffrey S.

Journal:

Year:

2002

Language:

english

File:

PDF, 226 KB

english, 2002

6

The transmembrane topology of the α subunit from the ATPase in Escherichia coli analyzed by PhoA protein fusions

Christian Bjørbæk, Vibeke Foërsom, Ole Michelsen

Journal:

Year:

1990

Language:

english

File:

PDF, 414 KB

english, 1990

7

Over-Expression of Leptin Receptors in Hypothalamic POMC Neurons Increases Susceptibility to Diet-Induced Obesity

Gamber, Kevin M., Huo, Lihong, Ha, Sangdeuk, Hairston, Joyce E., Greeley, Sarah, Bjørbæk, Christian, Irwin, Nigel

Journal:

Year:

2012

Language:

english

File:

PDF, 3.27 MB

english, 2012

8

Role of POMC and AgRP neuronal activities on glycaemia in mice

Üner, Aykut Göktürk, Keçik, Onur, Quaresma, Paula G. F., De Araujo, Thiago M., Lee, Hyon, Li, Wenjing, Kim, Hyun Jeong, Chung, Michelle, Bjørbæk, Christian, Kim, Young-Bum

Journal:

Scientific Reports

Year:

2019

File:

PDF, 5.88 MB

2019

9

Transcellular Transport of Leptin by the Short Leptin Receptor Isoform ObRa in Madin-Darby Canine Kidney Cells 1

Hileman, Stanley M., Tornøe, Jens, Flier, Jeffrey S., Bjørbæk, Christian

Journal:

Year:

2000

File:

PDF, 173 KB

2000

10

Activation of SOCS-3 Messenger Ribonucleic Acid in the Hypothalamus by Ciliary Neurotrophic Factor 1

Bjørbæk, Christian, Elmquist, Joel K., El-Haschimi, Karim, Kelly, Joseph, Ahima, Rexford S., Hileman, Stanley, Flier, Jeffrey S.

Journal:

Year:

1999

Language:

english

File:

PDF, 562 KB

english, 1999

11

Leptin-Dependent Control of Glucose Balance and Locomotor Activity by POMC Neurons

Lihong Huo, Kevin Gamber, Sarah Greeley, Jose Silva, Nicholas Huntoon, Xing-Hong Leng, Christian Bjørbæk

Journal:

Cell Metabolism

Year:

2009

Language:

english

File:

PDF, 1.22 MB

english, 2009

12

Central Leptin Receptor Action and Resistance in Obesity

Bjørbæk, Christian

Journal:

Journal of Investigative Medicine

Year:

2009

Language:

english

File:

PDF, 114 KB

english, 2009

13

Melanocortins Mimic the Effects of Leptin to Restore Reproductive Function in Lean Hypogonadotropic Ewes

Backholer, Kathryn, Bowden, Marissa, Gamber, Kevin, Bjørbæk, Christian, Iqbal, Javed, Clarke, Iain J.

Journal:

Neuroendocrinology

Year:

2010

Language:

english

File:

PDF, 1.01 MB

english, 2010

14

Leptin Differentially Regulates NPY and POMC Neurons Projecting to the Lateral Hypothalamic Area

Carol F Elias, Carl Aschkenasi, Charlotte Lee, Joseph Kelly, Rexford S Ahima, Christian Bjorbæk, Jeffrey S Flier, Clifford B Saper, Joel K Elmquist

Journal:

Year:

1999

Language:

english

File:

PDF, 228 KB

english, 1999

15

Role of Signal Transducer and Activator of Transcription 3 in Regulation of Hypothalamic Proopiomelanocortin Gene Expression by Leptin

Münzberg, Heike, Huo, Lihong, Nillni, Eduardo A., Hollenberg, Anthony N., Bjørbæk, Christian

Journal:

Year:

2003

Language:

english

File:

PDF, 684 KB

english, 2003

16

Identification and Characterization of Melanocortin-4 Receptor Gene Mutations in Morbidly Obese Finnish Children and Adults

Valli-Jaakola, Kaisa, Lipsanen-Nyman, Marita, Oksanen, Laura, Hollenberg, Anthony N., Kontula, Kimmo, Bjørbæk, Christian, Schalin-Jäntti, Camilla

Journal:

Journal of Clinical Endocrinology & Metabolism

Year:

2004

Language:

english

File:

PDF, 281 KB

english, 2004

17

Role of Signal Transducer and Activator of Transcription 3 in Regulation of Hypothalamic trh Gene Expression by Leptin

Huo, Lihong, Münzberg, Heike, Nillni, Eduardo A., Bjørbæk, Christian

Journal:

Year:

2004

Language:

english

File:

PDF, 346 KB

english, 2004

18

A widespread amino acid polymorphism at codon 905 of the glycogen-associated regulatory subunit of protein phosphatase-1 is associated with insulin resistance and hypersecretion of insulin

Hansen, Lars, Hansen, Torben, Vestergaard, Henrik, Bjørbæk, Christian, Echwald, Søren M., Clausen, Jesper O., Chen, Yu Hua, Chen, Mao Xiang, Cohen, Patricia T.W., Pedersen, Oluf

Journal:

Human Molecular Genetics

Year:

1995

Language:

english

File:

PDF, 2.49 MB

english, 1995

19

Functional Properties of Leptin Receptor Isoforms Containing the Gln→Pro Extracellular Domain Mutation of the Fatty Rat 1

da Silva, Barbara A., Bjørbæk, Christian, Uotani, Shigeo, Flier, Jeffrey S.

Journal:

Year:

1998

Language:

english

File:

PDF, 350 KB

english, 1998

20

Genetic Variants in Promoters and Coding Regions of the Muscle Glycogen Synthase and the Insulin-Responsive GLUT4 Genes in NIDDM

Bjørbæk, Christian, Echwald, Søren M, Hubricht, Peter, Vestergaard, Henrik, Hansen, Torben, Zierath, Juleen, Pedersen, Oluf

Journal:

Year:

1994

Language:

english

File:

PDF, 1.55 MB

english, 1994

21

Leptin and the Control of Food Intake: Neurons in the Nucleus of the Solitary Tract Are Activated by Both Gastric Distension and Leptin

Huo, Lihong, Maeng, Lisa, Bjørbæk, Christian, Grill, Harvey J.

Journal:

Year:

2007

Language:

english

File:

PDF, 873 KB

english, 2007

22

Divergent Leptin Signaling in Proglucagon Neurons of the Nucleus of the Solitary Tract in Mice and Rats

Huo, Lihong, Gamber, Kevin M., Grill, Harvey J., Bjørbæk, Christian

Journal:

Year:

2008

Language:

english

File:

PDF, 359 KB

english, 2008

23

Expression of Leptin Receptor Isoforms in Rat Brain Microvessels

Bjørbæk, Christian, Elmquist, Joel K., Michl, Patrick, Ahima, Rexford S., van Bueren, Antonia, McCall, Anthony L., Flier, Jeffrey S.

Journal:

Year:

1998

Language:

english

File:

PDF, 388 KB

english, 1998

24

[Vitamins & Hormones] Volume 65 || Leptin and melanocortin signaling in the hypothalamus

Bjørbæk, Christian

Year:

2002

Language:

english

File:

PDF, 2.50 MB

english, 2002

25

Divergent Functional Roles for p90 rsk Kinase Domains

Bjørbæk, Christian, Zhao, Yi, Moller, David E.

Journal:

Journal of Biological Chemistry

Year:

1995

File:

PDF, 5.77 MB

1995

26

Two defects contribute to hypothalamic leptin resistance in mice with diet-induced obesity

El-Haschimi, Karim, Pierroz, Dominique D., Hileman, Stanley M., Bjørbæk, Christian, Flier, Jeffrey S.

Journal:

Journal of Clinical Investigation

Year:

2000

Language:

english

File:

PDF, 648 KB

english, 2000

27

Hypothalamic Agouti-Related Peptide Neurons and the Central Melanocortin System Are Crucial Mediators of Leptin’s Antidiabetic Actions

Gonçalves, Gabriel H.M., Li, Wenjing, Garcia, Adriana V.C.-G., Figueiredo, Mariana S., Bjørbæk, Christian

Journal:

Year:

2014

Language:

english

File:

PDF, 893 KB

english, 2014

28

Transcellular Transport of Leptin by the Short Leptin Receptor Isoform ObRa in Madin-Darby Canine Kidney Cells 1

Hileman, Stanley M., Tornøe, Jens, Flier, Jeffrey S., Bjørbæk, Christian

Journal:

Year:

2000

Language:

english

File:

PDF, 173 KB

english, 2000

29

Somato-Dendritic Localization and Signaling by Leptin Receptors in Hypothalamic POMC and AgRP Neurons

Ha, Sangdeuk, Baver, Scott, Huo, Lihong, Gata, Adriana, Hairston, Joyce, Huntoon, Nicholas, Li, Wenjing, Zhang, Thompson, Benecchi, Elizabeth J., Ericsson, Maria, Hentges, Shane T., Bjørbæk, Christian

Journal:

Year:

2013

Language:

english

File:

PDF, 6.23 MB

english, 2013

30

Role of POMC and AgRP neuronal activities on glycaemia in mice

Üner, Aykut Göktürk, Keçik, Onur, Quaresma, Paula G. F., De Araujo, Thiago M., Lee, Hyon, Li, Wenjing, Kim, Hyun Jeong, Chung, Michelle, Bjørbæk, Christian, Kim, Young-Bum

Journal:

Scientific Reports

Year:

2019

Language:

english

File:

PDF, 5.88 MB

english, 2019

31

Enhanced leptin sensitivity and attenuation of diet-induced obesity in mice with haploinsufficiency of Socs3

Howard, Jane K, Cave, Belinda J, Oksanen, Laura J, Tzameli, Iphigenia, Bjørbæk, Christian, Flier, Jeffrey S

Journal:

Nature Medicine

Year:

2004

Language:

english

File:

PDF, 319 KB

english, 2004

32

Rho-kinase regulates energy balance by targeting hypothalamic leptin receptor signaling

Huang, Hu, Kong, Dong, Byun, Kyung Hee, Ye, Chianping, Koda, Shuichi, Lee, Dae Ho, Oh, Byung-Chul, Lee, Sam W, Lee, Bonghee, Zabolotny, Janice M, Kim, Min Seon, Bjørbæk, Christian, Lowell, Bradford B,

Journal:

Nature Neuroscience

Year:

2012

Language:

english

File:

PDF, 1.40 MB

english, 2012

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